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Majocchi’s Granuloma

Majocchi's Granuloma1

Majocchi's Granuloma2

General Information
Majocchi’s Granuloma is an uncommon infection of the dermal and subcutaneous tissue by dermatophytes. The most common cause of the infection is by a fungus called Trichophyton rubrum (an anthropophilic dermatophyte). Two forms of Majocchi’s granuloma exist: Follicular type – caused by trauma or a topical used, subcutaneous type – immunocompromised hosts. MG may be noted on any area where hair is involved, but is most often seen on the scalp, face, forearms, hands and legs. Treatment recommended by health-care professionals include systemic antifungal medications and topical medications.

Epidemiology
Commonly occurs in young women that shave their legs frequently

Etiology
Linked to Trichophyton Rubrum infection, also occurs when potent topical steroids are used on unsuspected tinea

Pathogenesis
Begins as a suppurative folliculitis and develops in a granulomatous reaction

Clinical
Nonpruitic solitary or multiple papulopustules or plaques

Histology
Demonstrates suppurative folliculitis to dense granulomatous infiltrates

Bibliography
1. “Majocchi Granuloma” (Online). July 2007. http://www.emedicine.com/DERM/topic849.htm (visited: March 24, 2008)

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